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N,N,N-trimethyl-2,3-bis(oleoyloxy)propan-1-aminium iodide

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  • IUPAC Name

    N,N,N-trimethyl-2,3-bis(oleoyloxy)propan-1-aminium iodide

  • Chemical Formula

    C₄₂H₈₂INO₄

  • Molecular Weight

    792.0

  • Form

    Solid

  • SMILES

    O=C(OCC(C[N+](C)(C)C)OC(CCCCCCC/C=C\CCCCCCCC)=O)CCCCCCC/C=C\CCCCCCCC.[I-]

  • Synonyms

    DOTAP iodide; 1,2-dioleoyl-3-trimethylammonium-propane iodide

N,N,N-Trimethyl-2,3-bis(oleoyloxy)propan-1-aminium iodide is a permanently cationic lipid with two fluid oleoyl chains and a trimethylammonium headgroup. It readily forms liposomes that interact with negatively charged biomolecules and is widely used in gene delivery, lipid research, and membrane biophysics.

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