IUPAC Name
N,N,N-trimethyl-2,3-bis(((9Z,12Z)-octadeca-9,12-dienoyl)oxy)propan-1-aminium iodide
Chemical Formula
C₄₂H₇₈INO₄
Molecular Weight
788.0
Form
Solid
SMILES
O=C(OCC(C[N+](C)(C)C)OC(CCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCCCC/C=C\C/C=C\CCCCC.[I-]
Synonyms
1,2-Dilinoeyl-3-trimethylammonium-propane iodide; DLiTAP iodide
N,N,N-Trimethyl-2,3-bis(((9Z,12Z)-octadeca-9,12-dienoyl)oxy)propan-1-aminium iodide (DLiTAP iodide) is a cationic lipid composed of a glycerol-based trimethylammonium headgroup and two linoleic acid tails. It forms highly fluid, positively charged bilayers, making it suitable for gene delivery, liposomal formulations, and membrane fusion research. Its polyunsaturated tails give it lower melting temperature and greater flexibility than its mono-unsaturated (DOTAP) or saturated analogues.
