IUPAC Name
2-((2,3-bis(oleoyloxy)propyl)dimethylammonio)acetate
Chemical Formula
C₄₁H₇₈NO₆
Molecular Weight
680
Form
Solid
SMILES
O=C(OCC(C[N+](C)(CC([O-])=O)C)OC(CCCCCCC/C=C\CCCCCCCC)=O)CCCCCCC/C=C\CCCCCCCC
2-((2,3-bis(oleoyloxy)propyl)dimethylammonio)acetate is a synthetic zwitterionic lipid and a structural analog of phosphatidylcholine (PC), one of the most abundant and biocompatible lipids found in cell membranes. Because of its neutral overall charge and unsaturated fatty acid tails, it forms fluid, biologically relevant bilayers, making it useful for liposome formation, membrane biophysics, and drug or gene delivery systems. It creates neutral or zwitterionic bilayers, improving stability and reducing cytotoxicity compared to cationic lipids, is used in lipid vesicles for encapsulating hydrophobic or hydrophilic drugs, Serves as a model lipid for studying membrane fluidity, permeability, and protein-lipid interactions and functions as a mild, biocompatible surfactant due to its amphiphilic nature.
