IUPAC Name
2,3-bis(hexadecyloxy)-N,N-dimethylpropan-1-amine
Chemical Formula
C₃₇H₈₁NO₂
Molecular Weight
588
Form
Solid
SMILES
CN(C)CC(COCCCCCCCCCCCCCCCC)OCCCCCCCCCCCCCCCC
AAPharmaSyn Stock ID
00036
2,3-Bis(hexadecyloxy)-N,N-dimethylpropan-1-amine is a synthetic cationic lipid molecule designed with a glycerol-like backbone, two long hydrophobic alkyl chains, and a tertiary amine headgroup. This combination makes it amphiphilic — possessing both hydrophobic and hydrophilic regions — allowing it to form lipid bilayers, vesicles, or lipoplexes for biological and materials applications. The tertiary amine can carry a positive charge that electrostatically binds negatively charged DNA or RNA, forming lipoplexes for transfection. The amphiphilic nature allows formation of lipid bilayers, liposomes, and nanostructures useful in drug delivery or synthetic membrane models. It acts as a cationic surfactant, stabilizing emulsions or dispersions in aqueous systems and is useful for surface modification, forming stable monolayers or coatings on negatively charged substrates.
