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2,3-bis(dodecanoyloxy)propyl (2-(trimethylammonio)ethyl) phosphate

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  • IUPAC Name

    2,3-bis(dodecanoyloxy)propyl (2-(trimethylammonio)ethyl) phosphate

  • Chemical Formula

    C₂₇H₅₆NO₈P

  • Molecular Weight

    554

  • Form

    Solid

  • SMILES

    O=C(OCC(COP(OCC[N+](C)(C)C)([O-])=O)OC(CCCCCCCCCCC)=O)CCCCCCCCCCC

  • AAPharmaSyn Stock ID

    00043

2,3-Bis(dodecanoyloxy)propyl (2-(trimethylammonio)ethyl) phosphate is a cationic phospholipid analog, structurally similar to DOTAP or other synthetic lipid derivatives, and is primarily used in experimental lipid formulations, drug/gene delivery, and membrane research. It is useful in lipid nanoparticle (LNP) formulations for hydrophobic drug encapsulation.

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